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    <link:label id="lab_iart_RestOfWorldMember_15A6B92A4AB2D9A966527472E8301E22_label_en-US" xlink:label="lab_iart_RestOfWorldMember_15A6B92A4AB2D9A966527472E8301E22" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Rest Of World [Member]</link:label>
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    <link:label id="lab_us-gaap_SegmentReportingInformationLineItems_660DF308A18F877D2D857472E8302CAB_label_en-US" xlink:label="lab_us-gaap_SegmentReportingInformationLineItems_660DF308A18F877D2D857472E8302CAB" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Segment Reporting Information [Line Items]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_660DF308A18F877D2D857472E8302CAB" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_660DF308A18F877D2D857472E8302CAB" xlink:to="lab_us-gaap_SegmentReportingInformationLineItems_660DF308A18F877D2D857472E8302CAB" xlink:type="arc" />
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_B2C8E866202D6BF9CEDF7472E83010C0_terseLabel_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_B2C8E866202D6BF9CEDF7472E83010C0" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total Revenues</link:label>
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_B2C8E866202D6BF9CEDF7472E83010C0_label_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_B2C8E866202D6BF9CEDF7472E83010C0" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Revenue from Contract with Customer, Excluding Assessed Tax</link:label>
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    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_B0E8CF926F4559638CE57472E929E6C6_label_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_B0E8CF926F4559638CE57472E929E6C6" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Goodwill and Intangible Assets Disclosure [Abstract]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_B0E8CF926F4559638CE57472E929E6C6" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_B0E8CF926F4559638CE57472E929E6C6" xlink:to="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_B0E8CF926F4559638CE57472E929E6C6" xlink:type="arc" />
    <link:label id="lab_us-gaap_GoodwillImpairmentLoss_D8771977C14C0A8B1BAE7472E9298148_terseLabel_en-US" xlink:label="lab_us-gaap_GoodwillImpairmentLoss_D8771977C14C0A8B1BAE7472E9298148" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Goodwill, impairment</link:label>
    <link:label id="lab_us-gaap_GoodwillImpairmentLoss_D8771977C14C0A8B1BAE7472E9298148_label_en-US" xlink:label="lab_us-gaap_GoodwillImpairmentLoss_D8771977C14C0A8B1BAE7472E9298148" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Goodwill, Impairment Loss</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_D8771977C14C0A8B1BAE7472E9298148" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GoodwillImpairmentLoss_D8771977C14C0A8B1BAE7472E9298148" xlink:to="lab_us-gaap_GoodwillImpairmentLoss_D8771977C14C0A8B1BAE7472E9298148" xlink:type="arc" />
    <link:label id="lab_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5_terseLabel_en-US" xlink:label="lab_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Intangible assets, indefinite lives, discount rate</link:label>
    <link:label id="lab_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5_label_en-US" xlink:label="lab_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Intangible Assets, Indefinite Life, Discount Rate, Percentage</link:label>
    <link:label id="lab_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5_documentation_en-US" xlink:label="lab_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Intangible Assets, Indefinite Life, Discount Rate, Percentage</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage" xlink:label="loc_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5" xlink:to="lab_iart_IntangibleAssetsIndefiniteLifeDiscountRatePercentage_2EC6A0118A1ADF3269237472E929E7D5" xlink:type="arc" />
    <link:label id="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5AD375CFCFA7DE6011F57472E92A8C03_terseLabel_en-US" xlink:label="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5AD375CFCFA7DE6011F57472E92A8C03" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Intangible assets, indefinite lives, impairment</link:label>
    <link:label id="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5AD375CFCFA7DE6011F57472E92A8C03_label_en-US" xlink:label="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5AD375CFCFA7DE6011F57472E92A8C03" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5AD375CFCFA7DE6011F57472E92A8C03" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5AD375CFCFA7DE6011F57472E92A8C03" xlink:to="lab_us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill_5AD375CFCFA7DE6011F57472E92A8C03" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_26722DF519F92ABA86497472E92A2955_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_26722DF519F92ABA86497472E92A2955" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, remainder of 2020</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_26722DF519F92ABA86497472E92A2955_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_26722DF519F92ABA86497472E92A2955" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_26722DF519F92ABA86497472E92A2955" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_26722DF519F92ABA86497472E92A2955" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_26722DF519F92ABA86497472E92A2955" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6B27BC93BC5FBF9147757472E92AA0A3_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6B27BC93BC5FBF9147757472E92AA0A3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2021</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6B27BC93BC5FBF9147757472E92AA0A3_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6B27BC93BC5FBF9147757472E92AA0A3" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year One</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6B27BC93BC5FBF9147757472E92AA0A3" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6B27BC93BC5FBF9147757472E92AA0A3" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6B27BC93BC5FBF9147757472E92AA0A3" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7482F57963E52C7BC70D7472E92A26D9_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7482F57963E52C7BC70D7472E92A26D9" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2022</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7482F57963E52C7BC70D7472E92A26D9_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7482F57963E52C7BC70D7472E92A26D9" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Two</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7482F57963E52C7BC70D7472E92A26D9" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7482F57963E52C7BC70D7472E92A26D9" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_7482F57963E52C7BC70D7472E92A26D9" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_670895250BE39E6CFBE67472E92AEF8A_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_670895250BE39E6CFBE67472E92AEF8A" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2023</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_670895250BE39E6CFBE67472E92AEF8A_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_670895250BE39E6CFBE67472E92AEF8A" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Three</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_670895250BE39E6CFBE67472E92AEF8A" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_670895250BE39E6CFBE67472E92AEF8A" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_670895250BE39E6CFBE67472E92AEF8A" xlink:type="arc" />
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    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_CCFCD4FF2CFF557E5C907472E92A3F19_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_CCFCD4FF2CFF557E5C907472E92A3F19" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Four</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_CCFCD4FF2CFF557E5C907472E92A3F19" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_CCFCD4FF2CFF557E5C907472E92A3F19" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_CCFCD4FF2CFF557E5C907472E92A3F19" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_6093D55EFAFE906F99777472E92BA373_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_6093D55EFAFE906F99777472E92BA373" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2025</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_6093D55EFAFE906F99777472E92BA373_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_6093D55EFAFE906F99777472E92BA373" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Asset, Expected Amortization, Year Five</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_6093D55EFAFE906F99777472E92BA373" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_6093D55EFAFE906F99777472E92BA373" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_6093D55EFAFE906F99777472E92BA373" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_A71B49AA38911035411E7472E92B0385_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_A71B49AA38911035411E7472E92B0385" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, thereafter</link:label>
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    <link:label id="lab_iart_ReturnPolicyIssueOfCreditNumberOfDaysFromShipment_AF8471DDC0958E1A415A7472E95EFC9B_terseLabel_en-US" xlink:label="lab_iart_ReturnPolicyIssueOfCreditNumberOfDaysFromShipment_AF8471DDC0958E1A415A7472E95EFC9B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Number of days from shipment to issue a credit</link:label>
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    <link:label id="lab_us-gaap_ContractWithCustomerLiabilityCurrent_41CEE7D7CC8018A2436C7472E95EF633_verboseLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiabilityCurrent_41CEE7D7CC8018A2436C7472E95EF633" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Short-term portion of contract liability</link:label>
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    <link:loc xlink:href="iart-20200930.xsd#iart_PaymentsToAcquireInProcessResearchAndDevelopmentMilestone" xlink:label="loc_iart_PaymentsToAcquireInProcessResearchAndDevelopmentMilestone_94033A4DC128E6AE443D7472EA266D9B" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ProceedsFromCollectionOfNotesReceivable_B7E197C1A50E5B90BEE87472EA26FAF5_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromCollectionOfNotesReceivable_B7E197C1A50E5B90BEE87472EA26FAF5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Proceeds from note receivable</link:label>
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    <link:label id="lab_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_E4F9C34188738C5E1A2B7472EA2604D3_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_E4F9C34188738C5E1A2B7472EA2604D3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Proceeds from sale of property and equipment</link:label>
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    <link:label id="lab_iart_AnnualRateOfLeaseAgreement_A35393D8BF8E3C1FEC857472E89BB391_terseLabel_en-US" xlink:label="lab_iart_AnnualRateOfLeaseAgreement_A35393D8BF8E3C1FEC857472E89BB391" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Annual rate of lease agreement</link:label>
    <link:label id="lab_iart_AnnualRateOfLeaseAgreement_A35393D8BF8E3C1FEC857472E89BB391_label_en-US" xlink:label="lab_iart_AnnualRateOfLeaseAgreement_A35393D8BF8E3C1FEC857472E89BB391" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Annual Rate Of Lease Agreement</link:label>
    <link:label id="lab_iart_AnnualRateOfLeaseAgreement_A35393D8BF8E3C1FEC857472E89BB391_documentation_en-US" xlink:label="lab_iart_AnnualRateOfLeaseAgreement_A35393D8BF8E3C1FEC857472E89BB391" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Annual rate of lease agreement.</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_AnnualRateOfLeaseAgreement" xlink:label="loc_iart_AnnualRateOfLeaseAgreement_A35393D8BF8E3C1FEC857472E89BB391" xlink:type="locator" />
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    <link:label id="lab_iart_OptionToExtendLeaseYears_93C54B8743E3CAF450757472E89B8B6F_terseLabel_en-US" xlink:label="lab_iart_OptionToExtendLeaseYears_93C54B8743E3CAF450757472E89B8B6F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Option to extend lease, years</link:label>
    <link:label id="lab_iart_OptionToExtendLeaseYears_93C54B8743E3CAF450757472E89B8B6F_label_en-US" xlink:label="lab_iart_OptionToExtendLeaseYears_93C54B8743E3CAF450757472E89B8B6F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Option To Extend Lease, Years</link:label>
    <link:label id="lab_iart_OptionToExtendLeaseYears_93C54B8743E3CAF450757472E89B8B6F_documentation_en-US" xlink:label="lab_iart_OptionToExtendLeaseYears_93C54B8743E3CAF450757472E89B8B6F" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Option to extend lease, years.</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_OptionToExtendLeaseYears" xlink:label="loc_iart_OptionToExtendLeaseYears_93C54B8743E3CAF450757472E89B8B6F" xlink:type="locator" />
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseOptionToExtend_793D54BFFC7689993C6E7472E89BABFC_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseOptionToExtend_793D54BFFC7689993C6E7472E89BABFC" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Period for extended lease</link:label>
    <link:label id="lab_us-gaap_LesseeOperatingLeaseOptionToExtend_793D54BFFC7689993C6E7472E89BABFC_label_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseOptionToExtend_793D54BFFC7689993C6E7472E89BABFC" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Lessee, Operating Lease, Option to Extend</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseOptionToExtend" xlink:label="loc_us-gaap_LesseeOperatingLeaseOptionToExtend_793D54BFFC7689993C6E7472E89BABFC" xlink:type="locator" />
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    <link:label id="lab_us-gaap_DebtDisclosureTextBlock_0BE208D6A7AD013662DB7472E9261535_terseLabel_en-US" xlink:label="lab_us-gaap_DebtDisclosureTextBlock_0BE208D6A7AD013662DB7472E9261535" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">DEBT</link:label>
    <link:label id="lab_us-gaap_DebtDisclosureTextBlock_0BE208D6A7AD013662DB7472E9261535_label_en-US" xlink:label="lab_us-gaap_DebtDisclosureTextBlock_0BE208D6A7AD013662DB7472E9261535" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Disclosure [Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_0BE208D6A7AD013662DB7472E9261535" xlink:type="locator" />
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    <link:label id="lab_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926_terseLabel_en-US" xlink:label="lab_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contract Asset</link:label>
    <link:label id="lab_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926_label_en-US" xlink:label="lab_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Change In Contract With Customer, Asset [Roll Forward]</link:label>
    <link:label id="lab_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926_documentation_en-US" xlink:label="lab_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Change In Contract With Customer, Asset [Roll Forward]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_ChangeInContractWithCustomerAssetRollForward" xlink:label="loc_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926" xlink:to="lab_iart_ChangeInContractWithCustomerAssetRollForward_9E1B0601948D15D874677472E9531926" xlink:type="arc" />
    <link:label id="lab_us-gaap_ContractWithCustomerAssetNet_1A00D7B7DFFB94C626397472E9531EE9_periodStartLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerAssetNet_1A00D7B7DFFB94C626397472E9531EE9" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xml:lang="en-US">Contract asset, Beginning of period</link:label>
    <link:label id="lab_us-gaap_ContractWithCustomerAssetNet_1A00D7B7DFFB94C626397472E9531EE9_label_en-US" xlink:label="lab_us-gaap_ContractWithCustomerAssetNet_1A00D7B7DFFB94C626397472E9531EE9" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract with Customer, Asset, after Allowance for Credit Loss</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerAssetNet" xlink:label="loc_us-gaap_ContractWithCustomerAssetNet_1A00D7B7DFFB94C626397472E9531EE9" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerAssetNet_1A00D7B7DFFB94C626397472E9531EE9" xlink:to="lab_us-gaap_ContractWithCustomerAssetNet_1A00D7B7DFFB94C626397472E9531EE9" xlink:type="arc" />
    <link:label id="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_7017587268DF16CDBF167472E953C394_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_7017587268DF16CDBF167472E953C394" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xml:lang="en-US">Transferred to trade receivable of contract asset included in beginning of the year contract asset</link:label>
    <link:label id="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_7017587268DF16CDBF167472E953C394_label_en-US" xlink:label="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_7017587268DF16CDBF167472E953C394" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract with Customer, Asset, Reclassified to Receivable</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerAssetReclassifiedToReceivable" xlink:label="loc_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_7017587268DF16CDBF167472E953C394" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_7017587268DF16CDBF167472E953C394" xlink:to="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_7017587268DF16CDBF167472E953C394" xlink:type="arc" />
    <link:label id="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_7FCBA25322D8D274FD797472E953648B_terseLabel_en-US" xlink:label="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_7FCBA25322D8D274FD797472E953648B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contract asset, net of transferred to trade receivables on contracts during the period</link:label>
    <link:label id="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_7FCBA25322D8D274FD797472E953648B_label_en-US" xlink:label="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_7FCBA25322D8D274FD797472E953648B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract With Customer, Asset, Net Of Reclassified To Receivable</link:label>
    <link:label id="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_7FCBA25322D8D274FD797472E953648B_documentation_en-US" xlink:label="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_7FCBA25322D8D274FD797472E953648B" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Contract With Customer, Asset, Net Of Reclassified To Receivable</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable" xlink:label="loc_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_7FCBA25322D8D274FD797472E953648B" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ContractWithCustomerAssetNet_B76653F6978FB3799B987472E9541372_periodEndLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerAssetNet_B76653F6978FB3799B987472E9541372" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xml:lang="en-US">Contract asset, End of Period</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerAssetNet" xlink:label="loc_us-gaap_ContractWithCustomerAssetNet_B76653F6978FB3799B987472E9541372" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerAssetNet_B76653F6978FB3799B987472E9541372" xlink:to="lab_us-gaap_ContractWithCustomerAssetNet_B76653F6978FB3799B987472E9541372" xlink:type="arc" />
    <link:label id="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_687FF0FA304B035A59B07472E954D4F6_terseLabel_en-US" xlink:label="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_687FF0FA304B035A59B07472E954D4F6" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contract Liability</link:label>
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    <link:label id="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_687FF0FA304B035A59B07472E954D4F6_documentation_en-US" xlink:label="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_687FF0FA304B035A59B07472E954D4F6" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Change In Contract With Customer, Liability [Roll Forward]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_ChangeInContractWithCustomerLiabilityRollForward" xlink:label="loc_iart_ChangeInContractWithCustomerLiabilityRollForward_687FF0FA304B035A59B07472E954D4F6" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ContractWithCustomerLiability_B22A2D60761B6ECCA5297472E9540307_periodStartLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiability_B22A2D60761B6ECCA5297472E9540307" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xml:lang="en-US">Contract liability, Beginning of Period</link:label>
    <link:label id="lab_us-gaap_ContractWithCustomerLiability_B22A2D60761B6ECCA5297472E9540307_label_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiability_B22A2D60761B6ECCA5297472E9540307" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract with Customer, Liability</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_B22A2D60761B6ECCA5297472E9540307" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_7F134FA5B1F5EA578DAF7472E954825A_negatedLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_7F134FA5B1F5EA578DAF7472E954825A" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Recognition of revenue included in beginning of year contract liability</link:label>
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    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_7F134FA5B1F5EA578DAF7472E954825A" xlink:to="lab_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_7F134FA5B1F5EA578DAF7472E954825A" xlink:type="arc" />
    <link:label id="lab_iart_ContractwithCustomerLiabilityNetOfRevenueRecognized_6E97702A843E6D6280837472E954D1FE_terseLabel_en-US" xlink:label="lab_iart_ContractwithCustomerLiabilityNetOfRevenueRecognized_6E97702A843E6D6280837472E954D1FE" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contract liability, net of revenue recognized on contracts during the period</link:label>
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    <link:loc xlink:href="iart-20200930.xsd#iart_ContractwithCustomerLiabilityNetOfRevenueRecognized" xlink:label="loc_iart_ContractwithCustomerLiabilityNetOfRevenueRecognized_6E97702A843E6D6280837472E954D1FE" xlink:type="locator" />
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    <link:label id="lab_iart_ContractWithCustomerLiabilityIncreaseDecreaseFromForeignCurrencyTranslation_9550A530674F141B0C2E7472E9544298_terseLabel_en-US" xlink:label="lab_iart_ContractWithCustomerLiabilityIncreaseDecreaseFromForeignCurrencyTranslation_9550A530674F141B0C2E7472E9544298" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Foreign currency translation</link:label>
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    <link:label id="lab_iart_CashFlowLesseeAbstract_249047136D11464A16117472E88F865C_documentation_en-US" xlink:label="lab_iart_CashFlowLesseeAbstract_249047136D11464A16117472E88F865C" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Cash Flow, Lessee [Abstract]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_CashFlowLesseeAbstract" xlink:label="loc_iart_CashFlowLesseeAbstract_249047136D11464A16117472E88F865C" xlink:type="locator" />
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    <link:label id="lab_us-gaap_OperatingLeasePayments_9BADF4B3BD81CD32E3A87472E88F57BC_terseLabel_en-US" xlink:label="lab_us-gaap_OperatingLeasePayments_9BADF4B3BD81CD32E3A87472E88F57BC" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Operating cash flows from operating leases</link:label>
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    <link:label id="lab_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_1ACF4FC9A061964E0F637472E88FDF59_terseLabel_en-US" xlink:label="lab_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_1ACF4FC9A061964E0F637472E88FDF59" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Operating leases</link:label>
    <link:label id="lab_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_1ACF4FC9A061964E0F637472E88FDF59_label_en-US" xlink:label="lab_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_1ACF4FC9A061964E0F637472E88FDF59" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Right-of-Use Asset Obtained in Exchange for Operating Lease Liability</link:label>
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    <link:label id="lab_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_2F49C73F132DF7A58D767472E8C7E72F_label_en-US" xlink:label="lab_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_2F49C73F132DF7A58D767472E8C7E72F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Prepaid Expenses and Other Current Assets [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember" xlink:label="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_2F49C73F132DF7A58D767472E8C7E72F" xlink:type="locator" />
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    <link:label id="lab_us-gaap_OtherAssetsMember_C66511D28E963E69622A7472E8C78A40_terseLabel_en-US" xlink:label="lab_us-gaap_OtherAssetsMember_C66511D28E963E69622A7472E8C78A40" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other assets</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsMember" xlink:label="loc_us-gaap_OtherAssetsMember_C66511D28E963E69622A7472E8C78A40" xlink:type="locator" />
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    <link:label id="lab_us-gaap_OtherLiabilitiesMember_F242626B07F1999BA8717472E8C836C3_terseLabel_en-US" xlink:label="lab_us-gaap_OtherLiabilitiesMember_F242626B07F1999BA8717472E8C836C3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other liabilities</link:label>
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    <link:label id="lab_iart_TrademarksBrandNamesMember_08C6FB10699BBCB081CE7472E931828B_documentation_en-US" xlink:label="lab_iart_TrademarksBrandNamesMember_08C6FB10699BBCB081CE7472E931828B" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Trademarks Brand Names.</link:label>
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    <link:label id="lab_iart_SupplierRelationShipsMember_72D14D6461DA11FA285B7472E93155E9_terseLabel_en-US" xlink:label="lab_iart_SupplierRelationShipsMember_72D14D6461DA11FA285B7472E93155E9" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Supplier relationships</link:label>
    <link:label id="lab_iart_SupplierRelationShipsMember_72D14D6461DA11FA285B7472E93155E9_label_en-US" xlink:label="lab_iart_SupplierRelationShipsMember_72D14D6461DA11FA285B7472E93155E9" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Supplier Relation Ships [Member]</link:label>
    <link:label id="lab_iart_SupplierRelationShipsMember_72D14D6461DA11FA285B7472E93155E9_documentation_en-US" xlink:label="lab_iart_SupplierRelationShipsMember_72D14D6461DA11FA285B7472E93155E9" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Supplier Relation Ships [Member]</link:label>
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    <link:label id="lab_iart_AllOtherMember_CCAF2E2698FF02E834977472E932FEA5_label_en-US" xlink:label="lab_iart_AllOtherMember_CCAF2E2698FF02E834977472E932FEA5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">All Other [Member]</link:label>
    <link:label id="lab_iart_AllOtherMember_CCAF2E2698FF02E834977472E932FEA5_documentation_en-US" xlink:label="lab_iart_AllOtherMember_CCAF2E2698FF02E834977472E932FEA5" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">All Other [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_AllOtherMember" xlink:label="loc_iart_AllOtherMember_CCAF2E2698FF02E834977472E932FEA5" xlink:type="locator" />
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    <link:label id="lab_iart_TransferToAssetsHeldForSaleMember_66185B76BFF84DA1A7AF7472E93222CC_terseLabel_en-US" xlink:label="lab_iart_TransferToAssetsHeldForSaleMember_66185B76BFF84DA1A7AF7472E93222CC" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Transfer to assets held for sale (See Note 2. Assets Held for Sale)</link:label>
    <link:label id="lab_iart_TransferToAssetsHeldForSaleMember_66185B76BFF84DA1A7AF7472E93222CC_label_en-US" xlink:label="lab_iart_TransferToAssetsHeldForSaleMember_66185B76BFF84DA1A7AF7472E93222CC" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Transfer To Assets Held For Sale [Member]</link:label>
    <link:label id="lab_iart_TransferToAssetsHeldForSaleMember_66185B76BFF84DA1A7AF7472E93222CC_documentation_en-US" xlink:label="lab_iart_TransferToAssetsHeldForSaleMember_66185B76BFF84DA1A7AF7472E93222CC" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Transfer To Assets Held For Sale [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_TransferToAssetsHeldForSaleMember" xlink:label="loc_iart_TransferToAssetsHeldForSaleMember_66185B76BFF84DA1A7AF7472E93222CC" xlink:type="locator" />
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    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_A34C17E59549EE242D5C7472E9326547_terseLabel_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_A34C17E59549EE242D5C7472E9326547" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Indefinite-lived Intangible Assets [Axis]</link:label>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_A34C17E59549EE242D5C7472E9326547_label_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_A34C17E59549EE242D5C7472E9326547" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Indefinite-lived Intangible Assets [Axis]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_A34C17E59549EE242D5C7472E9326547" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_A34C17E59549EE242D5C7472E9326547" xlink:to="lab_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_A34C17E59549EE242D5C7472E9326547" xlink:type="arc" />
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_ABDCD7128A2EFA1C88857472E9328D9C_terseLabel_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_ABDCD7128A2EFA1C88857472E9328D9C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Indefinite-lived Intangible Assets, Major Class Name [Domain]</link:label>
    <link:label id="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_ABDCD7128A2EFA1C88857472E9328D9C_label_en-US" xlink:label="lab_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_ABDCD7128A2EFA1C88857472E9328D9C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Indefinite-lived Intangible Assets, Major Class Name [Domain]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_ABDCD7128A2EFA1C88857472E9328D9C" xlink:type="locator" />
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    <link:label id="lab_us-gaap_TradeNamesMember_7B903C64A844D26CE8937472E93237BB_terseLabel_en-US" xlink:label="lab_us-gaap_TradeNamesMember_7B903C64A844D26CE8937472E93237BB" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Codman tradename</link:label>
    <link:label id="lab_us-gaap_TradeNamesMember_7B903C64A844D26CE8937472E93237BB_label_en-US" xlink:label="lab_us-gaap_TradeNamesMember_7B903C64A844D26CE8937472E93237BB" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Trade Names [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TradeNamesMember" xlink:label="loc_us-gaap_TradeNamesMember_7B903C64A844D26CE8937472E93237BB" xlink:type="locator" />
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    <link:label id="lab_us-gaap_InProcessResearchAndDevelopmentMember_484C401BE5AE5E008B2D7472E9338C05_verboseLabel_en-US" xlink:label="lab_us-gaap_InProcessResearchAndDevelopmentMember_484C401BE5AE5E008B2D7472E9338C05" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">IPR&amp;D</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_484C401BE5AE5E008B2D7472E9338C05" xlink:type="locator" />
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    <link:label id="lab_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_8C67C67A36B56CFAB5317472E9337593_terseLabel_en-US" xlink:label="lab_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_8C67C67A36B56CFAB5317472E9337593" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Acquired Finite-Lived Intangible Assets [Line Items]</link:label>
    <link:label id="lab_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_8C67C67A36B56CFAB5317472E9337593_label_en-US" xlink:label="lab_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_8C67C67A36B56CFAB5317472E9337593" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Acquired Finite-Lived Intangible Assets [Line Items]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsLineItems_8C67C67A36B56CFAB5317472E9337593" xlink:type="locator" />
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    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_C38944A49EF617AECD7D7472E933096B_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_C38944A49EF617AECD7D7472E933096B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Weighted Average Life</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_C38944A49EF617AECD7D7472E933096B_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetUsefulLife_C38944A49EF617AECD7D7472E933096B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Asset, Useful Life</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_C38944A49EF617AECD7D7472E933096B" xlink:type="locator" />
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    <link:label id="lab_iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill_1BB1D18227B78D6D8BA77472E933A48E_terseLabel_en-US" xlink:label="lab_iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill_1BB1D18227B78D6D8BA77472E933A48E" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Cost</link:label>
    <link:label id="lab_iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill_1BB1D18227B78D6D8BA77472E933A48E_label_en-US" xlink:label="lab_iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill_1BB1D18227B78D6D8BA77472E933A48E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Cost Of Definite And Indefinite Lived Intangible Assets Gross Excluding Goodwill</link:label>
    <link:label id="lab_iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill_1BB1D18227B78D6D8BA77472E933A48E_documentation_en-US" xlink:label="lab_iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill_1BB1D18227B78D6D8BA77472E933A48E" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Cost Of Definite And Indefinite Lived Intangible Assets Gross Excluding Goodwill.</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill" xlink:label="loc_iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill_1BB1D18227B78D6D8BA77472E933A48E" xlink:type="locator" />
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    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_6EFAF9FCF775C5EC6E877472E9330CCE_negatedLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_6EFAF9FCF775C5EC6E877472E9330CCE" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Accumulated Amortization</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_6EFAF9FCF775C5EC6E877472E9330CCE_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_6EFAF9FCF775C5EC6E877472E9330CCE" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Accumulated Amortization</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_6EFAF9FCF775C5EC6E877472E9330CCE" xlink:type="locator" />
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    <link:label id="lab_iart_DefiniteAndIndefiniteLivedIntangibleAssetsNetExcludingGoodwill_3BE2FE8FC50F731FF0067472E93443BD_label_en-US" xlink:label="lab_iart_DefiniteAndIndefiniteLivedIntangibleAssetsNetExcludingGoodwill_3BE2FE8FC50F731FF0067472E93443BD" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Definite And Indefinite Lived Intangible Assets Net Excluding Goodwill</link:label>
    <link:label id="lab_iart_DefiniteAndIndefiniteLivedIntangibleAssetsNetExcludingGoodwill_3BE2FE8FC50F731FF0067472E93443BD_documentation_en-US" xlink:label="lab_iart_DefiniteAndIndefiniteLivedIntangibleAssetsNetExcludingGoodwill_3BE2FE8FC50F731FF0067472E93443BD" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Definite And Indefinite Lived Intangible Assets Net Excluding Goodwill.</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_DefiniteAndIndefiniteLivedIntangibleAssetsNetExcludingGoodwill" xlink:label="loc_iart_DefiniteAndIndefiniteLivedIntangibleAssetsNetExcludingGoodwill_3BE2FE8FC50F731FF0067472E93443BD" xlink:type="locator" />
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    <link:label id="lab_us-gaap_OtherIndefiniteLivedIntangibleAssets_457342ACEB17F54F678B7472E9341C6B_terseLabel_en-US" xlink:label="lab_us-gaap_OtherIndefiniteLivedIntangibleAssets_457342ACEB17F54F678B7472E9341C6B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other indefinite-lived intangible assets</link:label>
    <link:label id="lab_us-gaap_OtherIndefiniteLivedIntangibleAssets_457342ACEB17F54F678B7472E9341C6B_label_en-US" xlink:label="lab_us-gaap_OtherIndefiniteLivedIntangibleAssets_457342ACEB17F54F678B7472E9341C6B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Other Indefinite-lived Intangible Assets</link:label>
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    <link:label id="lab_iart_DebtCovenantPeriod7Member_3E2E6C1970D5CF7CE1447472E904965D_terseLabel_en-US" xlink:label="lab_iart_DebtCovenantPeriod7Member_3E2E6C1970D5CF7CE1447472E904965D" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">September 30, 2021 through June 30, 2022</link:label>
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    <link:label id="lab_iart_DebtCovenantPeriod7Member_3E2E6C1970D5CF7CE1447472E904965D_documentation_en-US" xlink:label="lab_iart_DebtCovenantPeriod7Member_3E2E6C1970D5CF7CE1447472E904965D" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Debt Covenant Period 7 [Member]</link:label>
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    <link:label id="lab_iart_DebtCovenantPeriod8Member_BDC3A7EB0E406FE0ACD87472E905FD7F_terseLabel_en-US" xlink:label="lab_iart_DebtCovenantPeriod8Member_BDC3A7EB0E406FE0ACD87472E905FD7F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">September 30, 2022 through June 30, 2023</link:label>
    <link:label id="lab_iart_DebtCovenantPeriod8Member_BDC3A7EB0E406FE0ACD87472E905FD7F_label_en-US" xlink:label="lab_iart_DebtCovenantPeriod8Member_BDC3A7EB0E406FE0ACD87472E905FD7F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Covenant Period 8 [Member]</link:label>
    <link:label id="lab_iart_DebtCovenantPeriod8Member_BDC3A7EB0E406FE0ACD87472E905FD7F_documentation_en-US" xlink:label="lab_iart_DebtCovenantPeriod8Member_BDC3A7EB0E406FE0ACD87472E905FD7F" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Debt Covenant Period 8 [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_DebtCovenantPeriod8Member" xlink:label="loc_iart_DebtCovenantPeriod8Member_BDC3A7EB0E406FE0ACD87472E905FD7F" xlink:type="locator" />
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    <link:label id="lab_iart_DebtCovenantPeriod9Member_C8F88DCAC8AD36EDE12A7472E905F885_terseLabel_en-US" xlink:label="lab_iart_DebtCovenantPeriod9Member_C8F88DCAC8AD36EDE12A7472E905F885" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">September 30, 2023 and the last day of each fiscal quarter thereafter</link:label>
    <link:label id="lab_iart_DebtCovenantPeriod9Member_C8F88DCAC8AD36EDE12A7472E905F885_label_en-US" xlink:label="lab_iart_DebtCovenantPeriod9Member_C8F88DCAC8AD36EDE12A7472E905F885" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Covenant Period 9 [Member]</link:label>
    <link:label id="lab_iart_DebtCovenantPeriod9Member_C8F88DCAC8AD36EDE12A7472E905F885_documentation_en-US" xlink:label="lab_iart_DebtCovenantPeriod9Member_C8F88DCAC8AD36EDE12A7472E905F885" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Debt Covenant Period 9 [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_DebtCovenantPeriod9Member" xlink:label="loc_iart_DebtCovenantPeriod9Member_C8F88DCAC8AD36EDE12A7472E905F885" xlink:type="locator" />
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    <link:label id="lab_iart_DebtInstrumentCovenantMaximumLeverageRatio_B974EA606F7B0D275DB37472E9069311_terseLabel_en-US" xlink:label="lab_iart_DebtInstrumentCovenantMaximumLeverageRatio_B974EA606F7B0D275DB37472E9069311" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Maximum Consolidated Total Leverage Ratio</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_DebtInstrumentCovenantMaximumLeverageRatio" xlink:label="loc_iart_DebtInstrumentCovenantMaximumLeverageRatio_B974EA606F7B0D275DB37472E9069311" xlink:type="locator" />
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    <link:label id="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_7A455E63F606C77C8E227472E9DEE3BA_terseLabel_en-US" xlink:label="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_7A455E63F606C77C8E227472E9DEE3BA" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Basis Of Presentation</link:label>
    <link:label id="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_7A455E63F606C77C8E227472E9DEE3BA_label_en-US" xlink:label="lab_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_7A455E63F606C77C8E227472E9DEE3BA" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Basis of Accounting, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_7A455E63F606C77C8E227472E9DEE3BA" xlink:type="locator" />
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    <link:label id="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_3A714AA4D454EE74947E7472E9DE4274_terseLabel_en-US" xlink:label="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_3A714AA4D454EE74947E7472E9DE4274" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Recently Issued Accounting Standards</link:label>
    <link:label id="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_3A714AA4D454EE74947E7472E9DE4274_label_en-US" xlink:label="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_3A714AA4D454EE74947E7472E9DE4274" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">New Accounting Pronouncements, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_3A714AA4D454EE74947E7472E9DE4274" xlink:type="locator" />
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    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_72BA797784CB856D84EA7472E9DE9071_terseLabel_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_72BA797784CB856D84EA7472E9DE9071" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Summary of Accounting Policies on Revenue Recognition and Shipping and Handling Fees</link:label>
    <link:label id="lab_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_72BA797784CB856D84EA7472E9DE9071_label_en-US" xlink:label="lab_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_72BA797784CB856D84EA7472E9DE9071" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Revenue from Contract with Customer [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_72BA797784CB856D84EA7472E9DE9071" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ExtendedProductWarrantyPolicy_F240431E1A51065AC9237472E9DE13FE_terseLabel_en-US" xlink:label="lab_us-gaap_ExtendedProductWarrantyPolicy_F240431E1A51065AC9237472E9DE13FE" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Product Warranties</link:label>
    <link:label id="lab_us-gaap_ExtendedProductWarrantyPolicy_F240431E1A51065AC9237472E9DE13FE_label_en-US" xlink:label="lab_us-gaap_ExtendedProductWarrantyPolicy_F240431E1A51065AC9237472E9DE13FE" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Extended Product Warranty, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ExtendedProductWarrantyPolicy" xlink:label="loc_us-gaap_ExtendedProductWarrantyPolicy_F240431E1A51065AC9237472E9DE13FE" xlink:type="locator" />
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueTransactionPriceMeasurementTaxExclusionPolicyTextBlock" xlink:label="loc_us-gaap_RevenueTransactionPriceMeasurementTaxExclusionPolicyTextBlock_D4C96F3CDEBBFF8D1EC57472E9DEFAE6" xlink:type="locator" />
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    <link:label id="lab_iart_BusinessCombinationAndAssetAcquisitionDisclosureTextBlock_97C948BADC75869F247F7472E9973DED_terseLabel_en-US" xlink:label="lab_iart_BusinessCombinationAndAssetAcquisitionDisclosureTextBlock_97C948BADC75869F247F7472E9973DED" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">BUSINESS DEVELOPMENT</link:label>
    <link:label id="lab_iart_BusinessCombinationAndAssetAcquisitionDisclosureTextBlock_97C948BADC75869F247F7472E9973DED_label_en-US" xlink:label="lab_iart_BusinessCombinationAndAssetAcquisitionDisclosureTextBlock_97C948BADC75869F247F7472E9973DED" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Business Combination And Asset Acquisition Disclosure [Text Block]</link:label>
    <link:label id="lab_iart_BusinessCombinationAndAssetAcquisitionDisclosureTextBlock_97C948BADC75869F247F7472E9973DED_documentation_en-US" xlink:label="lab_iart_BusinessCombinationAndAssetAcquisitionDisclosureTextBlock_97C948BADC75869F247F7472E9973DED" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Business Combination And Asset Acquisition Disclosure [Text Block]</link:label>
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    <link:label id="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_C6022C4761EF637D074C7472E9430FA8_terseLabel_en-US" xlink:label="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_C6022C4761EF637D074C7472E9430FA8" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Finished goods</link:label>
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    <link:label id="lab_srt_ProductOrServiceAxis_1807C326D7B2947006DC7472E94D4317_label_en-US" xlink:label="lab_srt_ProductOrServiceAxis_1807C326D7B2947006DC7472E94D4317" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Product and Service [Axis]</link:label>
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    <link:label id="lab_srt_ProductsAndServicesDomain_C70154913DCA350E7ACA7472E94DF16F_label_en-US" xlink:label="lab_srt_ProductsAndServicesDomain_C70154913DCA350E7ACA7472E94DF16F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Product and Service [Domain]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_C70154913DCA350E7ACA7472E94DF16F" xlink:type="locator" />
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    <link:label id="lab_iart_NeurosurgeryMember_7C5E7C7CA5569C1286727472E94D313E_terseLabel_en-US" xlink:label="lab_iart_NeurosurgeryMember_7C5E7C7CA5569C1286727472E94D313E" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Neurosurgery</link:label>
    <link:label id="lab_iart_NeurosurgeryMember_7C5E7C7CA5569C1286727472E94D313E_label_en-US" xlink:label="lab_iart_NeurosurgeryMember_7C5E7C7CA5569C1286727472E94D313E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Neurosurgery [Member]</link:label>
    <link:label id="lab_iart_NeurosurgeryMember_7C5E7C7CA5569C1286727472E94D313E_documentation_en-US" xlink:label="lab_iart_NeurosurgeryMember_7C5E7C7CA5569C1286727472E94D313E" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Neurosurgery [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_NeurosurgeryMember" xlink:label="loc_iart_NeurosurgeryMember_7C5E7C7CA5569C1286727472E94D313E" xlink:type="locator" />
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    <link:label id="lab_iart_InstrumentsMember_D6C6A5293CB1B803A98C7472E94EA60C_terseLabel_en-US" xlink:label="lab_iart_InstrumentsMember_D6C6A5293CB1B803A98C7472E94EA60C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Instruments</link:label>
    <link:label id="lab_iart_InstrumentsMember_D6C6A5293CB1B803A98C7472E94EA60C_label_en-US" xlink:label="lab_iart_InstrumentsMember_D6C6A5293CB1B803A98C7472E94EA60C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Instruments [Member]</link:label>
    <link:label id="lab_iart_InstrumentsMember_D6C6A5293CB1B803A98C7472E94EA60C_documentation_en-US" xlink:label="lab_iart_InstrumentsMember_D6C6A5293CB1B803A98C7472E94EA60C" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Instruments [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_InstrumentsMember" xlink:label="loc_iart_InstrumentsMember_D6C6A5293CB1B803A98C7472E94EA60C" xlink:type="locator" />
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    <link:label id="lab_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0_terseLabel_en-US" xlink:label="lab_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Wound Reconstruction and Care</link:label>
    <link:label id="lab_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0_label_en-US" xlink:label="lab_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Regenerative Skin And Wound [Member]</link:label>
    <link:label id="lab_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0_documentation_en-US" xlink:label="lab_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Regenerative Skin And Wound [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_RegenerativeSkinAndWoundMember" xlink:label="loc_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0" xlink:to="lab_iart_RegenerativeSkinAndWoundMember_52139B104F9A99A099907472E94E13C0" xlink:type="arc" />
    <link:label id="lab_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03_terseLabel_en-US" xlink:label="lab_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Extremity Orthopedics</link:label>
    <link:label id="lab_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03_label_en-US" xlink:label="lab_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Extremity Orthopedics [Member]</link:label>
    <link:label id="lab_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03_documentation_en-US" xlink:label="lab_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Extremity Orthopedics [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_ExtremityOrthopedicsMember" xlink:label="loc_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03" xlink:to="lab_iart_ExtremityOrthopedicsMember_6C5FED73F4392191B43E7472E94EED03" xlink:type="arc" />
    <link:label id="lab_iart_PrivateLabelMember_438065AD7CD2D1A1DAF07472E94ED6E4_terseLabel_en-US" xlink:label="lab_iart_PrivateLabelMember_438065AD7CD2D1A1DAF07472E94ED6E4" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Private Label</link:label>
    <link:label id="lab_iart_PrivateLabelMember_438065AD7CD2D1A1DAF07472E94ED6E4_label_en-US" xlink:label="lab_iart_PrivateLabelMember_438065AD7CD2D1A1DAF07472E94ED6E4" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Private Label [Member]</link:label>
    <link:label id="lab_iart_PrivateLabelMember_438065AD7CD2D1A1DAF07472E94ED6E4_documentation_en-US" xlink:label="lab_iart_PrivateLabelMember_438065AD7CD2D1A1DAF07472E94ED6E4" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Private Label [Member]</link:label>
    <link:loc xlink:href="iart-20200930.xsd#iart_PrivateLabelMember" xlink:label="loc_iart_PrivateLabelMember_438065AD7CD2D1A1DAF07472E94ED6E4" xlink:type="locator" />
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    <link:label id="lab_us-gaap_DisaggregationOfRevenueLineItems_B1B9E9D47900639A14AF7472E94E9369_label_en-US" xlink:label="lab_us-gaap_DisaggregationOfRevenueLineItems_B1B9E9D47900639A14AF7472E94E9369" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Disaggregation of Revenue [Line Items]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisaggregationOfRevenueLineItems" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_B1B9E9D47900639A14AF7472E94E9369" xlink:type="locator" />
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    <link:label id="lab_us-gaap_AssetsAbstract_DE7883ABE7E68B42F76A7472EA596838_terseLabel_en-US" xlink:label="lab_us-gaap_AssetsAbstract_DE7883ABE7E68B42F76A7472EA596838" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">ASSETS</link:label>
    <link:label id="lab_us-gaap_AssetsAbstract_DE7883ABE7E68B42F76A7472EA596838_label_en-US" xlink:label="lab_us-gaap_AssetsAbstract_DE7883ABE7E68B42F76A7472EA596838" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Assets [Abstract]</link:label>
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    <link:label id="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue_38C1F53D9416BE1876377472EA595B58_label_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsAtCarryingValue_38C1F53D9416BE1876377472EA595B58" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Cash and Cash Equivalents, at Carrying Value</link:label>
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    <link:label id="lab_us-gaap_OtherAssetsNoncurrent_E480C56B92C25F10AFDE7472EA60D6AF_terseLabel_en-US" xlink:label="lab_us-gaap_OtherAssetsNoncurrent_E480C56B92C25F10AFDE7472EA60D6AF" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other assets</link:label>
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