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  <xs:element id="iart_AssetAcquisitionMaximumContingentDevelopmentMilestonePaymentsIfCircumstancesMet" abstract="false" name="AssetAcquisitionMaximumContingentDevelopmentMilestonePaymentsIfCircumstancesMet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_ArkisBioSciencesInc.Member" abstract="true" name="ArkisBioSciencesInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_OneMonthEurodollarRateMember" abstract="true" name="OneMonthEurodollarRateMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsEmployeeVacation" abstract="false" name="DeferredTaxAssetsTaxDeferredExpenseCompensationandBenefitsEmployeeVacation" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_DebtCovenantPeriod3Member" abstract="true" name="DebtCovenantPeriod3Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedRightOfUseAssetOperatingLeases" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedRightOfUseAssetOperatingLeases" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation" abstract="false" name="ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_EffectiveIncomeTaxRateReconciliationDeductionIntercompanyInventoryPercent" abstract="false" name="EffectiveIncomeTaxRateReconciliationDeductionIntercompanyInventoryPercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="iart_InterestRateSwapDesignatedDecember132017Tranche3Member" abstract="true" name="InterestRateSwapDesignatedDecember132017Tranche3Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_PerformanceStockandContractStockMember" abstract="true" name="PerformanceStockandContractStockMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_DeferredTaxAssetMember" abstract="true" name="DeferredTaxAssetMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_SmithNephewUSDLimitedMember" abstract="true" name="SmithNephewUSDLimitedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_CashFlowLesseeAbstract" abstract="true" name="CashFlowLesseeAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="iart_ConcentrationRiskNumberofCustomersOverBenchmark" abstract="false" name="ConcentrationRiskNumberofCustomersOverBenchmark" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable" abstract="false" name="ContractWithCustomerAssetNetOfReclassifiedToReceivable" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsCapitalizedResearchAndDevelopment" abstract="false" name="DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsCapitalizedResearchAndDevelopment" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_RevenueProductWarrantyPeriod" abstract="false" name="RevenueProductWarrantyPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="iart_GainLossOnDispositionOfPropertyPlantEquipmentAndConstructionInProgress" abstract="false" name="GainLossOnDispositionOfPropertyPlantEquipmentAndConstructionInProgress" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_RevenueFromContractWithCustomerProductsShippedWithNoAlternativeUseAndRightOfPaymentForPerformanceManufacturingPeriod" abstract="false" name="RevenueFromContractWithCustomerProductsShippedWithNoAlternativeUseAndRightOfPaymentForPerformanceManufacturingPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="iart_FoundationPolicyTextBlock" abstract="false" name="FoundationPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedAssetsAcquiredIncludingGoodwill" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedAssetsAcquiredIncludingGoodwill" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_CrossCurrencyInterestRateSwapContractThreeMember" abstract="true" name="CrossCurrencyInterestRateSwapContractThreeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_FairValueMeasurementwithUnobservableInputsReconciliationLiabilityTransfersFromLongTermtoCurrent" abstract="false" name="FairValueMeasurementwithUnobservableInputsReconciliationLiabilityTransfersFromLongTermtoCurrent" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_EffectiveWorldwideIncomeTaxRateReconciliationPercent" abstract="false" name="EffectiveWorldwideIncomeTaxRateReconciliationPercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="iart_RelatedPartiesMember" abstract="true" name="RelatedPartiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_NeurosurgeryMember" abstract="true" name="NeurosurgeryMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_DefiniteAndIndefiniteLivedIntangibleAssetsNetExcludingGoodwill" abstract="false" name="DefiniteAndIndefiniteLivedIntangibleAssetsNetExcludingGoodwill" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_DebtCovenantPeriod1Member" abstract="true" name="DebtCovenantPeriod1Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_AccountingStandardUpdate202006Member" abstract="true" name="AccountingStandardUpdate202006Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_DefinedBenefitPlanDeferPaymentAndTaxationBaseSalaryPercentage" abstract="false" name="DefinedBenefitPlanDeferPaymentAndTaxationBaseSalaryPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="iart_PaymentsToAcquireInProcessResearchAndDevelopmentAndIntangibleAssets" abstract="false" name="PaymentsToAcquireInProcessResearchAndDevelopmentAndIntangibleAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_TermLoanFacilityMember" abstract="true" name="TermLoanFacilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_IncomeTaxTable" abstract="true" name="IncomeTaxTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="iart_FiveYearLeasePeriodTwoMember" abstract="true" name="FiveYearLeasePeriodTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_DebtCovenantPeriod2Member" abstract="true" name="DebtCovenantPeriod2Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_EffectiveIncomeTaxRateReconciliationAssetsHeldForSaleOutsideBasisDifferencePercent" abstract="false" name="EffectiveIncomeTaxRateReconciliationAssetsHeldForSaleOutsideBasisDifferencePercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="iart_ReboundTherapeuticsCorporationMember" abstract="true" name="ReboundTherapeuticsCorporationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_CrossCurrencyInterestRateContractOneMember" abstract="true" name="CrossCurrencyInterestRateContractOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccruedExpenses" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccruedExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayableAccruedExpensesAndOtherLiabilities" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayableAccruedExpensesAndOtherLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_ScheduleOfAssetAcquisitionTable" abstract="true" name="ScheduleOfAssetAcquisitionTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsAdjustmentsforPerformanceAchievementWeightedAverageGrantDateFairValue" abstract="false" name="SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsAdjustmentsforPerformanceAchievementWeightedAverageGrantDateFairValue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="iart_DebtInstrumentCombinationSettlementForDebtConversionMinimumSettledInCashPerPrincipalAmount" abstract="false" name="DebtInstrumentCombinationSettlementForDebtConversionMinimumSettledInCashPerPrincipalAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_CodmanSpecialtySurgicalMember" abstract="true" name="CodmanSpecialtySurgicalMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_LesseeOperatingLeaseNumberOfRenewalOptions" abstract="false" name="LesseeOperatingLeaseNumberOfRenewalOptions" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="iart_OneMonthUSDLIBORMember" abstract="true" name="OneMonthUSDLIBORMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_DeferredTaxLiabilitiesLeasesAndOther" abstract="false" name="DeferredTaxLiabilitiesLeasesAndOther" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_InterestRateSwapDesignatedDecember182018Tranche2Member" abstract="true" name="InterestRateSwapDesignatedDecember182018Tranche2Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_OptionToExtendLeaseYears" abstract="false" name="OptionToExtendLeaseYears" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="iart_AllOtherMember" abstract="true" name="AllOtherMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_AssetAcquisitionAssetsAcquiredAndLiabilitiesAssumedNet" abstract="false" name="AssetAcquisitionAssetsAcquiredAndLiabilitiesAssumedNet" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedButNotIssuedInPeriod" abstract="false" name="SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedButNotIssuedInPeriod" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="iart_EffectiveIncomeTaxRateReconciliationDeferredIncomeTaxBenefitTransferIntraEntityIntellectualPropertyAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationDeferredIncomeTaxBenefitTransferIntraEntityIntellectualPropertyAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_CumulativeEffectPeriodOfAdoptionAdjustmentDebtDiscountReclassificationMember" abstract="true" name="CumulativeEffectPeriodOfAdoptionAdjustmentDebtDiscountReclassificationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill" abstract="false" name="CostOfDefiniteAndIndefiniteLivedIntangibleAssetsGrossExcludingGoodwill" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_CrossCurrencyInterestRateSwapContractOneMember" abstract="true" name="CrossCurrencyInterestRateSwapContractOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_EmployeeStockPurchasePlanProceeds" abstract="false" name="EmployeeStockPurchasePlanProceeds" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_SecuredLongTermDebtSecuritizationProgram" abstract="false" name="SecuredLongTermDebtSecuritizationProgram" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_ThirdPartiesMember" abstract="true" name="ThirdPartiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_SwinglineLoanMember" abstract="true" name="SwinglineLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_AssetAcquisitionNumberOfAssetsAcquired" abstract="false" name="AssetAcquisitionNumberOfAssetsAcquired" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="iart_SecuritizationFacilityFairValueOfAmountOutstanding" abstract="false" name="SecuritizationFacilityFairValueOfAmountOutstanding" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_IncreaseInAuthorizedShares" abstract="false" name="IncreaseInAuthorizedShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="iart_EffectiveIncomeTaxRateReconciliationTaxCreditForeignPerShare" abstract="false" name="EffectiveIncomeTaxRateReconciliationTaxCreditForeignPerShare" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="iart_InterestRateSwapDesignatedDecember132017Tranche1Member" abstract="true" name="InterestRateSwapDesignatedDecember132017Tranche1Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_MilestonePaymentOneMember" abstract="true" name="MilestonePaymentOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_InterestPaymentsYearTwo" abstract="false" name="InterestPaymentsYearTwo" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_IntegratedShoulderCollaborationInc.Member" abstract="true" name="IntegratedShoulderCollaborationInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_TwoThousandThreePlanMember" abstract="true" name="TwoThousandThreePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_IncomeTaxLineItems" abstract="true" name="IncomeTaxLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="iart_SecuredLongTermDebtSecuritizationProgramCurrent" abstract="false" name="SecuredLongTermDebtSecuritizationProgramCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_DisposalGroupIncludingDiscontinuedOperationLeaseLiabilityCurrent" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationLeaseLiabilityCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_NetWorkingCapital" abstract="false" name="NetWorkingCapital" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsVestedbutNotReleasedinPeriodWeightedAverageGrantDateFairValue" abstract="false" name="SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsVestedbutNotReleasedinPeriodWeightedAverageGrantDateFairValue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="iart_InstrumentsMember" abstract="true" name="InstrumentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_InterestRateSwapDesignatedMarch272017Member" abstract="true" name="InterestRateSwapDesignatedMarch272017Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_ContingentConsiderationLiabilityMember" abstract="true" name="ContingentConsiderationLiabilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_DisposalGroupIncludingDiscontinuedOperationRightOfUseAssetOperatingLeasesAndOtherAssets" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationRightOfUseAssetOperatingLeasesAndOtherAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_EffectiveIncomeTaxRateReconciliationTaxCutsAndJobsActOf2017GlobalIntangibleLowTaxedIncomePercent" abstract="false" name="EffectiveIncomeTaxRateReconciliationTaxCutsAndJobsActOf2017GlobalIntangibleLowTaxedIncomePercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="iart_DefinedBenefitPlanPlanAssetsPremiumsPaid" abstract="false" name="DefinedBenefitPlanPlanAssetsPremiumsPaid" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_DebtInstrumentMaximumSellingPriceOfCommonStockOfTheConversionPriceDuringPeriod" abstract="false" name="DebtInstrumentMaximumSellingPriceOfCommonStockOfTheConversionPriceDuringPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="iart_DebtInstrumentMaximumAverageConversionValueOfNotes" abstract="false" name="DebtInstrumentMaximumAverageConversionValueOfNotes" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="iart_CrossCurrencyInterestRateSwapContractTwoMember" abstract="true" name="CrossCurrencyInterestRateSwapContractTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="iart_DebtCovenantPeriod4Member" abstract="true" name="DebtCovenantPeriod4Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
