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    <link:label id="lab_iart_AcceleratedShareRepurchasesPercentageOfExpectedTotalRepurchased_CBCAE481D70AE57B4AAFD68ECEF8B273_terseLabel_en-US" xlink:label="lab_iart_AcceleratedShareRepurchasesPercentageOfExpectedTotalRepurchased_CBCAE481D70AE57B4AAFD68ECEF8B273" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Accelerated share repurchases, percentage of expected total repurchased</link:label>
    <link:label id="lab_iart_AcceleratedShareRepurchasesPercentageOfExpectedTotalRepurchased_CBCAE481D70AE57B4AAFD68ECEF8B273_label_en-US" xlink:label="lab_iart_AcceleratedShareRepurchasesPercentageOfExpectedTotalRepurchased_CBCAE481D70AE57B4AAFD68ECEF8B273" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Accelerated Share Repurchases, Percentage Of Expected Total Repurchased</link:label>
    <link:label id="lab_iart_AcceleratedShareRepurchasesPercentageOfExpectedTotalRepurchased_CBCAE481D70AE57B4AAFD68ECEF8B273_documentation_en-US" xlink:label="lab_iart_AcceleratedShareRepurchasesPercentageOfExpectedTotalRepurchased_CBCAE481D70AE57B4AAFD68ECEF8B273" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Accelerated Share Repurchases, Percentage Of Expected Total Repurchased</link:label>
    <link:loc xlink:href="iart-20200331.xsd#iart_AcceleratedShareRepurchasesPercentageOfExpectedTotalRepurchased" xlink:label="loc_iart_AcceleratedShareRepurchasesPercentageOfExpectedTotalRepurchased_CBCAE481D70AE57B4AAFD68ECEF8B273" xlink:type="locator" />
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    <link:label id="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_C7A513A7C24541193AD1D68ECEF9B790_terseLabel_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_C7A513A7C24541193AD1D68ECEF9B790" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Remaining amount under share repurchase</link:label>
    <link:label id="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_C7A513A7C24541193AD1D68ECEF9B790_label_en-US" xlink:label="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_C7A513A7C24541193AD1D68ECEF9B790" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Stock Repurchase Program, Remaining Authorized Repurchase Amount</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1" xlink:label="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_C7A513A7C24541193AD1D68ECEF9B790" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_C7A513A7C24541193AD1D68ECEF9B790" xlink:to="lab_us-gaap_StockRepurchaseProgramRemainingAuthorizedRepurchaseAmount1_C7A513A7C24541193AD1D68ECEF9B790" xlink:type="arc" />
    <link:label id="lab_us-gaap_InventoryNetAbstract_91E8CEF928D72E1B1420D68ED11F4C1D_label_en-US" xlink:label="lab_us-gaap_InventoryNetAbstract_91E8CEF928D72E1B1420D68ED11F4C1D" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Inventory, Net [Abstract]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryNetAbstract" xlink:label="loc_us-gaap_InventoryNetAbstract_91E8CEF928D72E1B1420D68ED11F4C1D" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryNetAbstract_91E8CEF928D72E1B1420D68ED11F4C1D" xlink:to="lab_us-gaap_InventoryNetAbstract_91E8CEF928D72E1B1420D68ED11F4C1D" xlink:type="arc" />
    <link:label id="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_11E1B7AAADCBA497629BD68ED1204758_terseLabel_en-US" xlink:label="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_11E1B7AAADCBA497629BD68ED1204758" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Finished goods</link:label>
    <link:label id="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_11E1B7AAADCBA497629BD68ED1204758_label_en-US" xlink:label="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_11E1B7AAADCBA497629BD68ED1204758" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Inventory, Finished Goods, Net of Reserves</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_11E1B7AAADCBA497629BD68ED1204758" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_11E1B7AAADCBA497629BD68ED1204758" xlink:to="lab_us-gaap_InventoryFinishedGoodsNetOfReserves_11E1B7AAADCBA497629BD68ED1204758" xlink:type="arc" />
    <link:label id="lab_us-gaap_InventoryWorkInProcessNetOfReserves_C76E792EB919C095B7ABD68ED120C0EA_terseLabel_en-US" xlink:label="lab_us-gaap_InventoryWorkInProcessNetOfReserves_C76E792EB919C095B7ABD68ED120C0EA" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Work in process</link:label>
    <link:label id="lab_us-gaap_InventoryWorkInProcessNetOfReserves_C76E792EB919C095B7ABD68ED120C0EA_label_en-US" xlink:label="lab_us-gaap_InventoryWorkInProcessNetOfReserves_C76E792EB919C095B7ABD68ED120C0EA" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Inventory, Work in Process, Net of Reserves</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryWorkInProcessNetOfReserves" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_C76E792EB919C095B7ABD68ED120C0EA" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryWorkInProcessNetOfReserves_C76E792EB919C095B7ABD68ED120C0EA" xlink:to="lab_us-gaap_InventoryWorkInProcessNetOfReserves_C76E792EB919C095B7ABD68ED120C0EA" xlink:type="arc" />
    <link:label id="lab_us-gaap_InventoryRawMaterialsAndPurchasedPartsNetOfReserves_BE7A13304C243AEEB68BD68ED12098BE_terseLabel_en-US" xlink:label="lab_us-gaap_InventoryRawMaterialsAndPurchasedPartsNetOfReserves_BE7A13304C243AEEB68BD68ED12098BE" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Raw materials</link:label>
    <link:label id="lab_us-gaap_InventoryRawMaterialsAndPurchasedPartsNetOfReserves_BE7A13304C243AEEB68BD68ED12098BE_label_en-US" xlink:label="lab_us-gaap_InventoryRawMaterialsAndPurchasedPartsNetOfReserves_BE7A13304C243AEEB68BD68ED12098BE" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Inventory, Raw Materials and Purchased Parts, Net of Reserves</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryRawMaterialsAndPurchasedPartsNetOfReserves" xlink:label="loc_us-gaap_InventoryRawMaterialsAndPurchasedPartsNetOfReserves_BE7A13304C243AEEB68BD68ED12098BE" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryRawMaterialsAndPurchasedPartsNetOfReserves_BE7A13304C243AEEB68BD68ED12098BE" xlink:to="lab_us-gaap_InventoryRawMaterialsAndPurchasedPartsNetOfReserves_BE7A13304C243AEEB68BD68ED12098BE" xlink:type="arc" />
    <link:label id="lab_us-gaap_InventoryNet_A949609957E554C2716ED68ED12138F9_totalLabel_en-US" xlink:label="lab_us-gaap_InventoryNet_A949609957E554C2716ED68ED12138F9" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Inventories, net</link:label>
    <link:label id="lab_us-gaap_InventoryNet_A949609957E554C2716ED68ED12138F9_label_en-US" xlink:label="lab_us-gaap_InventoryNet_A949609957E554C2716ED68ED12138F9" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Inventory, Net</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_A949609957E554C2716ED68ED12138F9" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryNet_A949609957E554C2716ED68ED12138F9" xlink:to="lab_us-gaap_InventoryNet_A949609957E554C2716ED68ED12138F9" xlink:type="arc" />
    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_85EC7BDD7E26C94A1465D68ED0F5C8B5_label_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_85EC7BDD7E26C94A1465D68ED0F5C8B5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Goodwill and Intangible Assets Disclosure [Abstract]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_85EC7BDD7E26C94A1465D68ED0F5C8B5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_85EC7BDD7E26C94A1465D68ED0F5C8B5" xlink:to="lab_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_85EC7BDD7E26C94A1465D68ED0F5C8B5" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_D3914C86CEF28F02C425D68ED0F5AFC2_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_D3914C86CEF28F02C425D68ED0F5AFC2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, remainder of 2020</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_D3914C86CEF28F02C425D68ED0F5AFC2_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_D3914C86CEF28F02C425D68ED0F5AFC2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Remainder of Fiscal Year</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_D3914C86CEF28F02C425D68ED0F5AFC2" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_D3914C86CEF28F02C425D68ED0F5AFC2" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_D3914C86CEF28F02C425D68ED0F5AFC2" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_EE8FAEEA99097DBF235FD68ED0F5D097_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_EE8FAEEA99097DBF235FD68ED0F5D097" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2021</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_EE8FAEEA99097DBF235FD68ED0F5D097_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_EE8FAEEA99097DBF235FD68ED0F5D097" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Two</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_EE8FAEEA99097DBF235FD68ED0F5D097" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_EE8FAEEA99097DBF235FD68ED0F5D097" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_EE8FAEEA99097DBF235FD68ED0F5D097" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_B93C95D1CBD87BAA64A2D68ED0F57A48_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_B93C95D1CBD87BAA64A2D68ED0F57A48" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2022</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_B93C95D1CBD87BAA64A2D68ED0F57A48_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_B93C95D1CBD87BAA64A2D68ED0F57A48" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Three</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_B93C95D1CBD87BAA64A2D68ED0F57A48" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_B93C95D1CBD87BAA64A2D68ED0F57A48" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_B93C95D1CBD87BAA64A2D68ED0F57A48" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_A5AC837EDF2497444644D68ED0F50887_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_A5AC837EDF2497444644D68ED0F50887" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2023</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_A5AC837EDF2497444644D68ED0F50887_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_A5AC837EDF2497444644D68ED0F50887" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Four</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_A5AC837EDF2497444644D68ED0F50887" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_A5AC837EDF2497444644D68ED0F50887" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_A5AC837EDF2497444644D68ED0F50887" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0F395A17BAE44C9AA688D68ED0F5C5F4_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0F395A17BAE44C9AA688D68ED0F5C5F4" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2024</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0F395A17BAE44C9AA688D68ED0F5C5F4_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0F395A17BAE44C9AA688D68ED0F5C5F4" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Five</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0F395A17BAE44C9AA688D68ED0F5C5F4" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0F395A17BAE44C9AA688D68ED0F5C5F4" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_0F395A17BAE44C9AA688D68ED0F5C5F4" xlink:type="arc" />
    <link:label id="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_BC98C936DBEE54A83C8AD68ED0F5E57F_terseLabel_en-US" xlink:label="lab_iart_FiniteLivedIntangibleAssetsAmortizationExpenseYearSix_BC98C936DBEE54A83C8AD68ED0F5E57F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Expected annual amortization expense, in 2025</link:label>
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    <link:label id="lab_us-gaap_CommitmentsAndContingencies_CFB05C1681418693870AD68ED248CF6F_label_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingencies_CFB05C1681418693870AD68ED248CF6F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Commitments and Contingencies</link:label>
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_07FB2380BCD5C546610CD68ECF376393_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_07FB2380BCD5C546610CD68ECF376393" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2020</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_07FB2380BCD5C546610CD68ECF376393" xlink:type="locator" />
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_5B34069267E5A39FC8D3D68ECF38DB90_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_5B34069267E5A39FC8D3D68ECF38DB90" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2020</link:label>
    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_5B34069267E5A39FC8D3D68ECF38DB90_label_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_5B34069267E5A39FC8D3D68ECF38DB90" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Lessee, Operating Lease, Liability, Payments, Remainder of Fiscal Year</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_5B34069267E5A39FC8D3D68ECF38DB90" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_5B34069267E5A39FC8D3D68ECF38DB90" xlink:to="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_5B34069267E5A39FC8D3D68ECF38DB90" xlink:type="arc" />
    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_E7EA4CC2C39AF1E1598AD68ECF38CCE8_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_E7EA4CC2C39AF1E1598AD68ECF38CCE8" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2021</link:label>
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_69A086573596751BC4B0D68ECF38DA3D_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_69A086573596751BC4B0D68ECF38DA3D" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2022</link:label>
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_2A5FE64FF5141A86CB78D68ECF38DE0E_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_2A5FE64FF5141A86CB78D68ECF38DE0E" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2023</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetNet" xlink:label="loc_us-gaap_ContractWithCustomerAssetNet_4A9D0A5D9948CFA9413DD68ED18B8CF9" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerAssetNet_4A9D0A5D9948CFA9413DD68ED18B8CF9" xlink:to="lab_us-gaap_ContractWithCustomerAssetNet_4A9D0A5D9948CFA9413DD68ED18B8CF9" xlink:type="arc" />
    <link:label id="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_61601E5E00CBE70F0E5CD68ED18C855C_negatedTerseLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_61601E5E00CBE70F0E5CD68ED18C855C" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="resource" xml:lang="en-US">Transferred to trade receivable of contract asset included in beginning of the year contract asset</link:label>
    <link:label id="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_61601E5E00CBE70F0E5CD68ED18C855C_label_en-US" xlink:label="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_61601E5E00CBE70F0E5CD68ED18C855C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract with Customer, Asset, Reclassified to Receivable</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetReclassifiedToReceivable" xlink:label="loc_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_61601E5E00CBE70F0E5CD68ED18C855C" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_61601E5E00CBE70F0E5CD68ED18C855C" xlink:to="lab_us-gaap_ContractWithCustomerAssetReclassifiedToReceivable_61601E5E00CBE70F0E5CD68ED18C855C" xlink:type="arc" />
    <link:label id="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B_terseLabel_en-US" xlink:label="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contract asset, net of transferred to trade receivables on contracts during the period</link:label>
    <link:label id="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B_label_en-US" xlink:label="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract With Customer, Asset, Net Of Reclassified To Receivable</link:label>
    <link:label id="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B_documentation_en-US" xlink:label="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Contract With Customer, Asset, Net Of Reclassified To Receivable</link:label>
    <link:loc xlink:href="iart-20200331.xsd#iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable" xlink:label="loc_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B" xlink:to="lab_iart_ContractWithCustomerAssetNetOfReclassifiedToReceivable_57E8BC2929AD1F6B7075D68ED18C300B" xlink:type="arc" />
    <link:label id="lab_us-gaap_ContractWithCustomerAssetNet_91DE737E5974DC3BEC8BD68ED18C5D76_periodEndLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerAssetNet_91DE737E5974DC3BEC8BD68ED18C5D76" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xml:lang="en-US">Contract asset, End of Period</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerAssetNet" xlink:label="loc_us-gaap_ContractWithCustomerAssetNet_91DE737E5974DC3BEC8BD68ED18C5D76" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerAssetNet_91DE737E5974DC3BEC8BD68ED18C5D76" xlink:to="lab_us-gaap_ContractWithCustomerAssetNet_91DE737E5974DC3BEC8BD68ED18C5D76" xlink:type="arc" />
    <link:label id="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618_terseLabel_en-US" xlink:label="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contract Liability</link:label>
    <link:label id="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618_label_en-US" xlink:label="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Change In Contract With Customer, Liability [Roll Forward]</link:label>
    <link:label id="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618_documentation_en-US" xlink:label="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Change In Contract With Customer, Liability [Roll Forward]</link:label>
    <link:loc xlink:href="iart-20200331.xsd#iart_ChangeInContractWithCustomerLiabilityRollForward" xlink:label="loc_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618" xlink:to="lab_iart_ChangeInContractWithCustomerLiabilityRollForward_0BE82B50EF521E809206D68ED18C9618" xlink:type="arc" />
    <link:label id="lab_us-gaap_ContractWithCustomerLiability_99625D16C03F6F72EEAED68ED18D2748_periodStartLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiability_99625D16C03F6F72EEAED68ED18D2748" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xml:lang="en-US">Contract liability, Beginning of Period</link:label>
    <link:label id="lab_us-gaap_ContractWithCustomerLiability_99625D16C03F6F72EEAED68ED18D2748_label_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiability_99625D16C03F6F72EEAED68ED18D2748" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract with Customer, Liability</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_99625D16C03F6F72EEAED68ED18D2748" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerLiability_99625D16C03F6F72EEAED68ED18D2748" xlink:to="lab_us-gaap_ContractWithCustomerLiability_99625D16C03F6F72EEAED68ED18D2748" xlink:type="arc" />
    <link:label id="lab_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4ECA9C1EF1077C24B28CD68ED18DFA80_negatedLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4ECA9C1EF1077C24B28CD68ED18DFA80" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="resource" xml:lang="en-US">Recognition of revenue included in beginning of year contract liability</link:label>
    <link:label id="lab_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4ECA9C1EF1077C24B28CD68ED18DFA80_label_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4ECA9C1EF1077C24B28CD68ED18DFA80" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract with Customer, Liability, Revenue Recognized</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiabilityRevenueRecognized" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4ECA9C1EF1077C24B28CD68ED18DFA80" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4ECA9C1EF1077C24B28CD68ED18DFA80" xlink:to="lab_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_4ECA9C1EF1077C24B28CD68ED18DFA80" xlink:type="arc" />
    <link:label id="lab_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A_terseLabel_en-US" xlink:label="lab_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contract liability, net of revenue recognized on contracts during the period</link:label>
    <link:label id="lab_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A_label_en-US" xlink:label="lab_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract With Customer, Liability, Net Of Revenue Recognized And Foreign Currency Translation</link:label>
    <link:label id="lab_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A_documentation_en-US" xlink:label="lab_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Contract With Customer, Liability, Net Of Revenue Recognized And Foreign Currency Translation</link:label>
    <link:loc xlink:href="iart-20200331.xsd#iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation" xlink:label="loc_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A" xlink:to="lab_iart_ContractWithCustomerLiabilityNetOfRevenueRecognizedAndForeignCurrencyTranslation_6C6D28F5E6D9F5D998D8D68ED18D934A" xlink:type="arc" />
    <link:label id="lab_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA_terseLabel_en-US" xlink:label="lab_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Foreign currency translation</link:label>
    <link:label id="lab_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA_label_en-US" xlink:label="lab_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Contract With Customer, Liability, Increase From Foreign Currency Translation</link:label>
    <link:label id="lab_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA_documentation_en-US" xlink:label="lab_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Contract With Customer, Liability, Increase From Foreign Currency Translation</link:label>
    <link:loc xlink:href="iart-20200331.xsd#iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation" xlink:label="loc_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA" xlink:to="lab_iart_ContractWithCustomerLiabilityIncreaseFromForeignCurrencyTranslation_E41C691CA7B73B49A8BED68ED18D46CA" xlink:type="arc" />
    <link:label id="lab_us-gaap_ContractWithCustomerLiability_16F3532BD7C284DCA8C6D68ED18E54B4_periodEndLabel_en-US" xlink:label="lab_us-gaap_ContractWithCustomerLiability_16F3532BD7C284DCA8C6D68ED18E54B4" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xml:lang="en-US">Contract liability, End of Period</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_16F3532BD7C284DCA8C6D68ED18E54B4" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ContractWithCustomerLiability_16F3532BD7C284DCA8C6D68ED18E54B4" xlink:to="lab_us-gaap_ContractWithCustomerLiability_16F3532BD7C284DCA8C6D68ED18E54B4" xlink:type="arc" />
    <link:label id="lab_iart_CodmanSpecialtySurgicalMember_04901A1E30B3F8E7A3E0D68ECE0CE23F_verboseLabel_en-US" xlink:label="lab_iart_CodmanSpecialtySurgicalMember_04901A1E30B3F8E7A3E0D68ECE0CE23F" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Codman Specialty Surgical</link:label>
    <link:loc xlink:href="iart-20200331.xsd#iart_CodmanSpecialtySurgicalMember" xlink:label="loc_iart_CodmanSpecialtySurgicalMember_04901A1E30B3F8E7A3E0D68ECE0CE23F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_iart_CodmanSpecialtySurgicalMember_04901A1E30B3F8E7A3E0D68ECE0CE23F" xlink:to="lab_iart_CodmanSpecialtySurgicalMember_04901A1E30B3F8E7A3E0D68ECE0CE23F" xlink:type="arc" />
    <link:label id="lab_srt_ConsolidationItemsAxis_B255DA257906A7E3FBB0D68ECE0CF767_terseLabel_en-US" xlink:label="lab_srt_ConsolidationItemsAxis_B255DA257906A7E3FBB0D68ECE0CF767" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Consolidation Items [Axis]</link:label>
    <link:label id="lab_srt_ConsolidationItemsAxis_B255DA257906A7E3FBB0D68ECE0CF767_label_en-US" xlink:label="lab_srt_ConsolidationItemsAxis_B255DA257906A7E3FBB0D68ECE0CF767" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Consolidation Items [Axis]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="loc_srt_ConsolidationItemsAxis_B255DA257906A7E3FBB0D68ECE0CF767" xlink:type="locator" />
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    <link:label id="lab_srt_ConsolidationItemsDomain_B0B99611208550EE3084D68ECE0CC92D_terseLabel_en-US" xlink:label="lab_srt_ConsolidationItemsDomain_B0B99611208550EE3084D68ECE0CC92D" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Operating Activities [Domain]</link:label>
    <link:label id="lab_srt_ConsolidationItemsDomain_B0B99611208550EE3084D68ECE0CC92D_label_en-US" xlink:label="lab_srt_ConsolidationItemsDomain_B0B99611208550EE3084D68ECE0CC92D" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Consolidation Items [Domain]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="loc_srt_ConsolidationItemsDomain_B0B99611208550EE3084D68ECE0CC92D" xlink:type="locator" />
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    <link:label id="lab_us-gaap_OperatingSegmentsMember_316F1B757DA51FE03DE8D68ECE129443_terseLabel_en-US" xlink:label="lab_us-gaap_OperatingSegmentsMember_316F1B757DA51FE03DE8D68ECE129443" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Operating Segments</link:label>
    <link:label id="lab_us-gaap_OperatingSegmentsMember_316F1B757DA51FE03DE8D68ECE129443_label_en-US" xlink:label="lab_us-gaap_OperatingSegmentsMember_316F1B757DA51FE03DE8D68ECE129443" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Operating Segments [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_316F1B757DA51FE03DE8D68ECE129443" xlink:type="locator" />
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    <link:label id="lab_us-gaap_CorporateNonSegmentMember_1CE936478EFBED43EB84D68ECE12FC01_terseLabel_en-US" xlink:label="lab_us-gaap_CorporateNonSegmentMember_1CE936478EFBED43EB84D68ECE12FC01" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Corporate and other</link:label>
    <link:label id="lab_us-gaap_CorporateNonSegmentMember_1CE936478EFBED43EB84D68ECE12FC01_label_en-US" xlink:label="lab_us-gaap_CorporateNonSegmentMember_1CE936478EFBED43EB84D68ECE12FC01" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Corporate, Non-Segment [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CorporateNonSegmentMember" xlink:label="loc_us-gaap_CorporateNonSegmentMember_1CE936478EFBED43EB84D68ECE12FC01" xlink:type="locator" />
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    <link:label id="lab_iart_DebtAccountsReceivableSecuritizationTerm_86FED59D5E862BE94815D68ED0DF499C_terseLabel_en-US" xlink:label="lab_iart_DebtAccountsReceivableSecuritizationTerm_86FED59D5E862BE94815D68ED0DF499C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Securitization program, term</link:label>
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    <link:label id="lab_iart_DebtAccountsReceivableSecuritizationTerm_86FED59D5E862BE94815D68ED0DF499C_documentation_en-US" xlink:label="lab_iart_DebtAccountsReceivableSecuritizationTerm_86FED59D5E862BE94815D68ED0DF499C" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Debt, Accounts Receivable Securitization, Term</link:label>
    <link:loc xlink:href="iart-20200331.xsd#iart_DebtAccountsReceivableSecuritizationTerm" xlink:label="loc_iart_DebtAccountsReceivableSecuritizationTerm_86FED59D5E862BE94815D68ED0DF499C" xlink:type="locator" />
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    <link:label id="lab_iart_DebtWeightedAverageInterestRateFromSecuritization_A3DDCB74BC3AE599DB47D68ED0E0B33B_terseLabel_en-US" xlink:label="lab_iart_DebtWeightedAverageInterestRateFromSecuritization_A3DDCB74BC3AE599DB47D68ED0E0B33B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Weighted average interest rate, accounts receivable securitization revolving loan facility</link:label>
    <link:label id="lab_iart_DebtWeightedAverageInterestRateFromSecuritization_A3DDCB74BC3AE599DB47D68ED0E0B33B_label_en-US" xlink:label="lab_iart_DebtWeightedAverageInterestRateFromSecuritization_A3DDCB74BC3AE599DB47D68ED0E0B33B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt, Weighted Average Interest Rate, From Securitization</link:label>
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    <link:label id="lab_iart_SecuritizationFacilityFairValueOfAmountOutstanding_4E7EFCA57EE33DA6FAB0D68ED0E09B8A_terseLabel_en-US" xlink:label="lab_iart_SecuritizationFacilityFairValueOfAmountOutstanding_4E7EFCA57EE33DA6FAB0D68ED0E09B8A" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Securitization facility, outstanding borrowings, fair value</link:label>
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    <link:label id="lab_iart_SecuritizationFacilityFairValueOfAmountOutstanding_4E7EFCA57EE33DA6FAB0D68ED0E09B8A_documentation_en-US" xlink:label="lab_iart_SecuritizationFacilityFairValueOfAmountOutstanding_4E7EFCA57EE33DA6FAB0D68ED0E09B8A" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Securitization Facility, Fair Value Of Amount Outstanding</link:label>
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